Synthetic methods of organic chemistry. Volume 14 (Theilheimer, W.; Karger, S.)

Synthetic Organic Chemistry

Synthetic biology: lessons from the history of synthetic organic chemistry.

The mid-nineteenth century saw the development of a radical new direction in chemistry: instead of simply analyzing existing molecules, chemists began to synthesize them--including molecules that did not exist in nature. The combination of this new synthetic approach with more traditional analytical approaches revolutionized chemistry, leading to a deep understanding of the fundamental principl...

Lecture 2 : Karger ’ s Min Cut Algorithm

(These notes are a slightly modified version of notes from previous offerings of the class scribed by Sanjeev.) Today’s topic is simple but gorgeous: Karger’s min cut algorithm and its extension. It is a simple randomized algorithm for finding the minimum cut in a graph: a subset of vertices S in which the set of edges leaving S, denoted E(S, S) has minimum size among all subsets. You may have ...

on Karger ’ s Min - Cut Algorithm

Traditionally, the min-cut problem was solved by solving n − 1 min-st-cut problems. In the min-st-cut problem we are given as input two vertices s and t, our aim is to find the set S where s ∈ S and t / ∈ S which minimizes the size of the cut (S, S), i.e., |δ(S)|. The size of the min-st-cut is equal to the value of the max-st-flow (equivalent by linear programming duality). The fastest algorith...

Half-Century Journey from Synthetic Organic Chemistry to Mathematical Stereochemistry through Chemoinformatics

My half-century journey started from synthetic organic chemistry. During the first stage of my journey, my interest in stereochemistry was initiated through the investigation on the participation of steric effects in reactive intermediates, cylophanes, strained heterocycles, and organic compounds for photography. In chemoinformatics as the next stage of the journey, I proposed the concept of im...